Table 3.
Comparison of follicular and serum concentrations of free radicals and antioxidant enzyme activity between the two groups
| Free radicals and antioxidant enzymes variables | GnRH agonist group | GnRH antagonist group | P |
|---|---|---|---|
| (n = 39) | (n = 45) | ||
| Serum concentrations | |||
| Antioxidant enzymes activities | |||
| SOD (U/ml) | 6.62 ± 2.21 | 8.24 ± 2.05 | 0.001* |
| GSH-Px (U/l) | 157.51 ± 40.06 | 140.17 ± 38.88 | 0.048* |
| ADA (U/l) | 121.87 ± 40.39 | 123.42 ± 34.94 | NSa |
| XO (U/ml) | 0.15 ± 0.077 | 0.12 ± 0.059 | NSa |
| GSH (micromole/l) | 18.63 ± 14.70 | 11.66 ± 6.09 | 0.001* |
| Free radicals concentrations | |||
| MDA (micromole/l) | 0.90 ± 0.42 | 0.68 ± 0.41 | 0.003* |
| NO (micromole/l) | 19.07 ± 9.81 | 19.33 ± 6.95 | NSa |
| PC (micromole/dl) | 23.10 ± 9.76 | 24.87 ± 10.41 | NSa |
| OH-proline (mg/l) | 34.89 ± 2.78 | 34.04 ± 3.15 | NSa |
| Follicular concentrations | |||
| Antioxidant enzymes activities | |||
| SOD (U/l) | 11.75 ± 1.76 | 13.78 ± 2.16 | <0.001* |
| GSH-Px (U/g protein) | 84.58 ± 36.30 | 92.97 ± 44.81 | NSa |
| ADA (U/l) | 61.41 ± 37.23 | 84.04 ± 41.01 | 0.021* |
| XO (U/ml) | 0.079 ± 0.043 | 0.084 ± 0.084 | NSa |
| GSH (micromole/l) | 15.21 ± 7.06 | 13.94 ± 9.05 | NSa |
| Free radicals concentrations | |||
| MDA (micromole/l) | 0.48 ± 0.31 | 0.60 ± 0.46 | NSa |
| NO (micromole/l) | 18.77 ± 13.42 | 42.50 ± 34.80 | <0.001* |
| PC (micromole/dl) | 8.79 ± 5.37 | 10.98 ± 6.35 | NSa |
| OH-proline (mg/l) | 33.69 ± 8.34 | 29.83 ± 9.83 | <0.001* |
Values are mean ± standard deviation unless otherwise stated
*Statistically significant (p value <0.05)
aNot significant