Table 1.
Clinical and biochemical characteristics of hemodialysis patients and the control group
| Control group | HD | |
|---|---|---|
| Age (years) | 47.26 ± 14.54 | 58.64 ± 14.64 |
| RRF (ml) | NA | 510 (0.3100) |
| Time on HD (months) | NA | 52.57 ± 51.06 |
| Kt/V | NA | 1.15 ± 0.24 |
| Hemoglobin (g/dl) | 14.56 ± 2.86 | 11.33 ± 1.27*** |
| Cholesterol (mg/dl) | 206.15 ± 35.27 | 193.15 ± 50.96 |
| HDL (mg/dl) | NA | 41.74 ± 12.78 |
| LDL (mg/dl) | NA | 121.57 ± 44.86 |
| Triglycerides (mg/dl) | 98.36 ± 37.71 | 157.58 ± 81.23** |
| pH | NA | 7.36 ± 0.05 |
| Bicarbonates (mmol/l) | NA | 19.31 ± 3.32 |
| ESA dose (IU/week) | NA | 2000 (0–12000) |
| IL-6 (pg/ml) | 1.05 (0.1, 5.87) | 4.88 (0.1, 73.64)*** |
| TNF alpha (pg/ml) | 2.08 (0.01–5.00) | 13.90 (0.1–134.7)*** |
| hsCRP (mg/l) | 0.1 (0.1–2.5) | 5.20 (0.1, 21.1)*** |
| Iron (μg/dl) | 105.00 ± 34.95 | 72.22 ± 36.96* |
| TSAT (%) | 33.08 ± 11.91 | 33.98 ± 14.98 |
| TIBC (μg/dl) | 324.68 ± 55.67 | 246.53 ± 68.81* |
| Ferritin (ng/ml) | 75.63 ± 55.65 | 641.64 ± 353.01*** |
| sTfR (nmol/l) | 17.65 ± 4.60 | 31.89 ± 18.53* |
| Hepcidin (ng/ml) | 15.68 ± 11.83 | 54.03 ± 21.11*** |
| Hemojuvelin (mg/l) | 0.79 (0.21–1.10) | 2.72 (0.76–20.27)*** |
Data given are means ± SD, * P < 0.05, ** P < 0.01, *** P < 0.001