Figure 1.

Examples of familial clusters of exceptional longevity. The small pedigree on the left (A) shows a sibship of three centenarians, with youngest age at death of 100 years. The pedigree on the right (B) shows a larger sibship of eight, with two centenarians (ages at death 101 and 106 years), three nonagenarians (ages 91, 93, and 94), and three siblings who live past the age of 80. Squares and circles represent males and females, diagonal bars represent deceased subjects. Numbers below nodes are birth years, last age at contact, and death year. For living subjects, the death year is not available (NA). Red triangles denote probands enrolled in the New England Centenarian Study.