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. 2012 Dec 13;1:e00070. doi: 10.7554/eLife.00070

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Copyright © 2012, Santoro and Dulac

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

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Figure 1. — Mouse H2BE is detected exclusively in chemosensory neurons. (A) Analysis of H2be mRNA in the MOE of an 8-week old mouse, showing expression limited to sensory neurons. Boxed region is magnified (right). (B) Analysis of H2be mRNA in the VNO of an 8-week old mouse, showing expression limited to sensory neurons, especially in the apical zone. (C) Analysis of H2be mRNA in a sagittal section of an E14.5 mouse embryo (image from genepaint.org; ID: ES2590). (D) Profile of H2be mRNA levels in 61 mouse tissues (listed, right), showing exclusive expression in MOE and VNO. Data from GNF, now maintained by BioGPS (http://biogps.org/). (E) Alignment of H2BE and canonical H2B sequences. H2BE variant positions are highlighted in red; H2B PTM sites supported by >5 or ≤5 reports are highlighted in dark and light gray, respectively (http://www.phosphosite.org). Scale bars for (A), 500 µm; (B), 100 µm; (C), 1000 µm.