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. 2012 Sep 21;40(21):10657–10667. doi: 10.1093/nar/gks860

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© The Author(s) 2012. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Network enrichments on the known molecular interactions during HCC progression. Significant enrichments were marked with asterisks. Network enrichments are significant for all five stages at network connectivity of 0.01 (26 connections), 0.02 (53 connections) and 0.03 (79 connections). Network enrichments remained to be significant for the four HCV-infected networks (cirrhotic, dysplastic, early HCC and advanced HCC) at network connectivity of 0.04 and 0.05. The highest enrichment was accomplished with a network connectivity of 0.01.