Fig 2.

Ex vivo contractile properties of NCoR1 MKO mouse skeletal muscle. (A to D) Ex vivo assessment of extensor digitorum longus (EDL) and soleus (SOL) contractility in response to a single twitch or a maximal tetanic stimulation (n = 10 CON and n = 14 NCoR1 MKO muscles per group). (E and F) Ex vivo assessment of EDL and SOL fatigue resistance in response to repeated tetanic stimulation through a long- and short-interval protocol. The inset in panel F shows the section with significant differences (n = 10 CON and n = 14 MKO muscles per group). Values represent means ± SEM. P < 0.05 (*) and P < 0.01 (**) for CON versus MKO mice.