Table 3.
Synthesis of secondary metabolites in Streptomyces davawensis
| Type | Gene cluster | Compound which most likely is produced |
|---|---|---|
| Bacteriocin | BN159_1027...BN159_1041 | |
| Butyrolactone | BN159_4437...BN159_4443 | |
| Ectoine | BN159_6645...BN159_6653 | |
| Lantibiotic | BN159_7730...BN159_7752 | |
| NRPSa | BN159_5552...BN159_5613 | Melanin |
| NRPS | BN159_6018...BN159_6082 | Moenomycin |
| NRPS | BN159_7504...BN159_7544 | |
| NRPS | BN159_7971...BN159_8026 | Meilingmycin |
| Oligosaccharide | BN159_2334...BN159_2384 | Aclacinomycin |
| Other | BN159_0820...BN159_0862 | |
| Other | BN159_6747...BN159_6783 | |
| Other | BN159_6878...BN159_6920 | |
| PKSb (type 1) | BN159_1344...BN159_1381 | RK-682 (19) |
| PKS (type 3) | BN159_2002...BN159_2033 | |
| PKS (type 2) | BN159_2454...BN159_2482 | Oxytetracycline |
| PKS (type 1) | BN159_2472...BN159_2508 | Pyrrolomycin |
| PKS (type 2) | BN159_2498...BN159_2530 | Lankamycin/lankacidin |
| PKS (type 3) | BN159_5906...BN159_5930 | |
| PKS (type 3) | BN159_7364...BN159_7396 | Erythromycin |
| PKS (type 3) | BN159_7926...BN159_7957 | Furaquinocin A |
| PKS-NRPS MIX | BN159_2119...BN159_2158 | Tirandamycin |
| PKS-NRPS MIX | BN159_0658...BN159_0706 | Sanglifehrin A |
| PKS-NRPS MIX | BN159_5857...BN159_5906 | |
| Siderophore (?)c | BN159_2064...BN159_2088 | Geosmin |
| Siderophore | BN159_2640...BN159_2654 | 2-Methylisoborneol |
| Siderophore | BN159_5473...BN159_5494 | Desferrioxamine |
| Terpene | BN159_1431...BN159_1450 | |
| Terpene | BN159_1587...BN159_1611 | |
| Terpene/butyrolactone | BN159_2258...BN159_2301 | |
| Terpene/NRPS | BN159_3136...BN159_3188 | Albaflavenone |
| Terpene | BN159_79530...BN159_7981 | Furaquinocin A |
| Terpene/melanin | BN159_8242...BN159_8286 | |
| Vitamin analog | BN159_8007...BN159_8044 (?) | Roseoflavin |
a
NRPS, nonribosomal peptide synthetases.
b
PKS, polyketide synthases.
c
Question marks indicate hypothetical data.