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Abilities of CasG (Ro05820) and CasI (Ro05822) to catalyze the ATP-dependent transformation of various steroid substrates bearing isopentanoyl and isopropanoyl side chainsa
| Substrate | CasG | CasI |
|---|---|---|
| Cholate | + | − |
| Lithocholate | + | − |
| Deoxycholate | + | − |
| Chenodeoxycholate | + | − |
| 3β-Hydroxy-5-cholenate | + | − |
| 3β-Hydroxy-23,24-bisnor-5-cholenate | − | + |
| 3-Oxo-23,24-bisnor-4-cholenate | − | + |
+, transformed; −, not transformed.
