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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Lancet Neurol. 2012 Nov 2;11(12):1039–1047. doi: 10.1016/S1474-4422(12)70241-7

Figure 1. Regions of the cerebral white matter in which systolic blood pressure (A, B) and age (C, D) are associated with decreased fractional anisotropy and increased mean diffusivity.

Figure 1

The voxel-based regression included diffusion tensor imaging measures (fractional anisotropy or mean diffusivity) as the dependent variable, and age and systolic blood pressure as independent variables. Number of cigarettes smoked per day, hypertension treatment (presence or absence), intracranial volume, and sex were covariates.