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. Author manuscript; available in PMC: 2012 Nov 30.
Published in final edited form as: J Immunol. 2010 Sep 22;185(8):4705–4713. doi: 10.4049/jimmunol.1002276

Figure 1.

Figure 1

Perturbation of positive selection affects the sizes of naïve CD4+ T cell populations. A, Contour plots of FliC:I-Ab tetramer versus 2W:I-Ab tetramer staining for CD3high CD4+ CD8− (left) or CD8+CD4− (right) thymocytes from tetramer-enriched thymus samples from naïve B6 mice. Numbers on plots indicate the percentage of cells in each quadrant. B, Total CD3high CD4+ CD8− or CD8+ CD4− 2W:I-Ab+ (filled symbols), or FliC:I-Ab+ (open symbols) cells from thymus samples of individual B6 controls, B6 > H2-DMa−/− chimeras, or B6 > Y-Ae (B6 > 1P) chimeras. Numbers above each group represent its mean value. *** P-value < 0.001; ** P-value ≤ 0.01 (unpaired two-tailed Student’s t-test). Data are representative of five independent experiments.