Fig. 1.
Effect of pre-exposure to Plasmodium infection on the immune response to subsequent infections. (A) 7 days post priming (dpp) or (B) 14 dpp with P. berghei in naïve (Nv) or challenged (Ch) mosquitoes. (C) Effect of pre-challenge with P. falciparum on a second infection at 7 dpp. Plasmodium infections were evaluated 7 days after the second infection. Effect of eliminating the gut microbiota with oral antibiotics before the (D) first or (E) second challenge with P. berghei on a second infection 7 dpp. Each circle represents the number of parasites in an individual midgut, and the line indicates the median.