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. 2012 Oct 2;33(12):2558–2567. doi: 10.1093/carcin/bgs285

Fig. 5.

Fig. 5.

QLT-0267 treatment decreases LEF-1 and Snail expression and impairs in vitro invasive properties of fERG-BPH-1 cells. (A) Immunoblot analysis of fERG-BPH-1 cells after 48h treatment with DMSO (0) or the indicated doses of QLT-0267 for expression of ERG, ILK, Snail and LEF-1 using β-actin immunoblotting as a loading control. (B) Quantification of Matrigel invasion assay of cells treated as in A for 24h expressed as average number of migrated cells per field in 6 random fields ± standard error of the mean (* different than Mock, P < 0.01, † different than untreated fERG, P < 0.01).