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. 2012 Sep 4;21(24):5239–5245. doi: 10.1093/hmg/dds370

Figure 3.

Figure 3.

The SMARCB1 mutant 3′UTR alters mRNA stability. Relative mRNA expression levels of wild-type and mutant SMARCB1 3′untranslated regions in HEK293T cells. (A) Luciferase levels indicate the relative expression under the control of wild-type and c.*82C > T mutated SMARCB1 3′UTRs, normalized to transfection efficiency by GFP fluorescence *P < 0.01. (B) qRT–PCR of wild-type and mutant SMARCB1 3′UTR expression levels at 48 and 96 h post-transfection normalized to both GFP and GAPDH *P < 0.015; **P < 0.001.