Figure 3.

Analysis of ploidy in nuclei from the cerebellum of young and old mice. (A) The picture summarizes the analysis of global ploidy on cerebellum nuclei performed for chromosomes 1, 7 and 18, one of the least and of the most aneuploid chromosome founded previously in the cortex. The analysis demonstrates that the accumulation of aneuploidy during aging in the cerebellum for the chromosomes tested is absent. (B) Aneuploidy frequencies for single chromosomes 1,7 and 18 also show a lack of individual significant increase during aging.