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. 2012 Oct 4;14(5):e125. doi: 10.2196/jmir.2102

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©Fahad Pervaiz, Mansoor Pervaiz, Nabeel Abdur Rehman, Umar Saif. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 04.10.2012.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on http://www.jmir.org/, as well as this copyright and license information must be included.

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Historical negative binomial cumulative sum (CUSUM) equation. k = reference value, S_n = CUSUM score, X_n = the case count of the current week, + superscript refers to values always being positive.