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. 2012 Oct 24;14(5):e131. doi: 10.2196/jmir.2056

Table 2.

Performance in outbreak detection according to germ criterion and a upper control limit defined by 90% confidence interval, with and without clustering.

Parameter Without clustering With clustering (d=0)g
Sensitivity (%)a 90.0 (27/30) 100 (30/30)
Specificity (%)b 84.0 (630/750) 86.7 (650/750)
PPV (%)c 18.4 (27/147) 23.1 (30/130)
NPV (%)d 99.5 (630/633) 100 (650/650)
AUCe (95% CIf) 0.87 (0.81-0.94) 0.93 (0.91-0.95)

a Sensitivity = TP/(TP+FN) (where TP (true positive) is an outbreak correctly identified as an outbreak, and FN (false negative) is an outbreak wrongly identified as a non-outbreak).

b Specificity = TN/(TN+FP) (where TN (true negative) is a non-outbreak correctly identified as a non-outbreak, and FP (false positive) is a non-outbreak wrongly identified as an outbreak).

c Positive predictive value (PPV) = TP/(TP+FP) (variables defined above).

d Negative predictive value (NPV) = TN/(TN+FN) (variables defined above).

e AUC: area under receiver operating characteristic curve.

f CI: confidence interval.

g d: cutting Euclidean distance.