Table 2.
Performance in outbreak detection according to germ criterion and a upper control limit defined by 90% confidence interval, with and without clustering.
| Parameter | Without clustering | With clustering (d=0)g |
| Sensitivity (%)a | 90.0 (27/30) | 100 (30/30) |
| Specificity (%)b | 84.0 (630/750) | 86.7 (650/750) |
| PPV (%)c | 18.4 (27/147) | 23.1 (30/130) |
| NPV (%)d | 99.5 (630/633) | 100 (650/650) |
| AUCe (95% CIf) | 0.87 (0.81-0.94) | 0.93 (0.91-0.95) |
a Sensitivity = TP/(TP+FN) (where TP (true positive) is an outbreak correctly identified as an outbreak, and FN (false negative) is an outbreak wrongly identified as a non-outbreak).
b Specificity = TN/(TN+FP) (where TN (true negative) is a non-outbreak correctly identified as a non-outbreak, and FP (false positive) is a non-outbreak wrongly identified as an outbreak).
c Positive predictive value (PPV) = TP/(TP+FP) (variables defined above).
d Negative predictive value (NPV) = TN/(TN+FN) (variables defined above).
e AUC: area under receiver operating characteristic curve.
f CI: confidence interval.
g d: cutting Euclidean distance.