Table 3.

 Risks of incident comorbidity after diagnosis of branch retinal vein occlusion (BRVO). Figures are numbers (percentage) of participants and incidence rate ratios (95% confidence intervals)

	BRVO cases	Controls	IRR (95%CI)*	P value
Hypertension†	188 (30)	14 688 (17)	1.37 (1.15 to 1.57)	<0.001
Diabetes†	52 (5.1)	2976 (2.8)	1.51 (1.17 to 2.04)	0.002
Myocardial infarction	61 (5.7)	3381 (3.1)	1.24 (0.97 to 1.62)	0.10
Congestive heart failure	96 (8.9)	4401 (4.0)	1.41 (1.12 to 1.68)	0.001
Ischaemic heart disease	123 (12)	7532 (7.2)	1.21 (0.97 to 1.41)	0.11
Peripheral artery disease	63 (6.0)	3375 (3.1)	1.26 (0.98 to 1.62)	0.10
Peripheral venous disease	24 (2.2)	1445 (1.3)	1.24 (0.83 to 1.86)	0.30
Cerebrovascular disease	145 (15)	6415 (6.0)	1.49 (1.27 to 1.76)	<0.001
Cardiovascular disease†‡	197 (33)	18 184 (22)	1.15 (0.99 to 1.32)	0.07

*Cox regression model estimating incidence rate ratio (IRR) with age as underlying timescale adjusted for sex and index year.

†Diagnoses based on hospital discharge diagnoses and drug prescriptions (remaining diagnoses based on hospital discharge diagnoses only).

‡Cardiovascular disease includes hypertension, cerebrovascular disease, ischaemic heart disease, congestive heart failure, peripheral vascular disease, and cardiovascular drugs.