FIGURE 7.

Summary of how and where different factors and receptors act during induction of exogenous reporter genes in assorted cell lines. For each cell line, the receptor for which there are data is given in parentheses below the cell name. The horizontal line with the CLS box in the middle represents the unidentified sequence of steps in gene induction that are at the CLS, before the CLS (i.e. to the left of the CLS), or after the CLS (i.e. to the right of the CLS). The range of steps at which each factor has been found to act in the present study relative to the CLS is indicated by the horizontal error bar or by a vertical equal symbol when the precise position is known. For each factor, how the factor acts (accelerator = A, competitive decelerator = C) is given in parentheses after the factor name, with the number 2 designating that competition occurs at two separate steps. The results with TIF2 and Ubc9 are from earlier reports (6, 8). See “Discussion” for additional details.