FIGURE 7.

FBXO44 expression in human breast tumors and matched non-tumor breast tissues and its correlation with BRCA1 expression. A, representative cases of breast carcinomas showed positive immunohistochemical staining of cancerous cells compared with negative staining of adjacent non-cancerous cells using anti-FBXO44. Original magnification, ×20. Scale bar, 100 μm. B, inverse correlation between FBXO44 and BRCA1 expression in human breast cancer samples. Representative immunohistochemical staining of FBXO44 and BRCA1 proteins was shown in the upper panel. A summary of 97 samples is shown in the lower panel. The p value was generated by Chi-square test. Original magnification, ×20. Scale bar, 100 μm.