TABLE 3.

Chemical structures and characteristics of small molecule inhibitors tested against Certhrax

^a The logP = log₁₀ (partition coefficient), partition coefficient = [compound]_octanol/[compound]_water and was calculated (clogP) using an on-line clogP calculator by ChemAxon Ltd.

^b,c The molecular weight (MW) (b) and logD pH (c) profiles were generated by the same on-line clogP calculator by ChemAxon Ltd. and represent the calculated log distribution coefficient, logD = log₁₀ (distribution coefficient) where distribution coefficient, D = [microspecies]_octanol/Σ[microspecies]_water.