TABLE 1.
Platelet analysis of dematin HPKO mice
Data are mean ± S.E. (n = 5). MPV, mean platelet volume; MFI, mean fluorescence intensity.
| Selected parameters | WT | HPKO |
|---|---|---|
| Platelet number (1000/μl) | 1416 + 145 | 1394 + 44 |
| Platelet volume (MPV) (fl) | 8.68 ± 0.17 | 8.8 ± 0.6 |
| Basal cAMP (pmol/108) platelets | 1.07 ± 0.27 | 1.17 ± 0.03 |
| Surface expression of integrin αIIbβ3 (MFI) | 28.4 ± 5.2 | 29.8 ± 3.4 |