FIGURE 2.

Neuritin did not alter the steady-state activation and inactivation properties of CGN I_A channels. A, I_A recorded using an activation protocol (see “Experimental Procedures”) from neurons maintained in control medium or medium containing 150 ng/ml neuritin. B, steady-state activation curves of I_A obtained by plotting the normalized conductance as a function of command potential obtained from control and neuritin-treated groups. Data points were fitted using the Boltzmann function. Data points are shown as means ± S.E. (error bars; n = 18 for the control group and n = 22 for the neuritin-treated group). C, steady-state inactivation curves for I_A obtained from control and neuritin-treated CGNs using inactivation protocols (see “Experimental Procedures”). Data points were fitted using the Boltzmann function. Data points are shown as means ± S.E. (n = 21 for the control group and n = 23 for the neuritin-treated group).