Table 1.

Thermodynamics of the inclusion of 4-tert-butyl-benzoate in β-cyclodextrin 1 and its methyl derivatives 2–6.

Host	No.	K (M−1)	ΔG° (kJ mol−1)	ΔH° (kJ mol−1)	−TΔS° (kJ mol−1)
unsubstituted β-CD	1	16400 ± 4	−24.34	−19.00 ± 0.08	−3.82
2,6-di-O-methyl-β-CD	2	17000 ± 485	−24.13	−19.98 ± 0.14	−4.18
2,3,6-tri-O-methyl-β-CD	3	1190 ± 21	−17.54	−30.54 ± 0.37	12.98
6-O-methyl-β-CD	4	30700 ± 898	−25.60	−20.14 ± 0.12	−5.49
2-O-methyl-β-CD	5	12300 ± 428	−23.33	−14.30 ± 0.11	−9.05
2,3-di-O-methyl-β-CD	6	869 ± 28	−16.77	−19.24 ± 0.84	+2.45
RAMEBa	7	14700 ± 363	−23.77	−14.60 ± 0.09	−9.20

^arandomly methylated β-CDs.