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. 2012 Nov 21;8:2025–2052. doi: 10.3762/bjoc.8.229

Scheme 25.

Scheme 25

Intermolecular [2 + 2] cycloaddition of maleimide (76) and intramolecular [2 + 2] cycloaddition of dimethylmaleimide derivative 78 under flow conditions.