Table 9.5.1.
Peptide Sequences for a Positional Scanning Hexapeptide Librarya
| Peptide mixture number | Peptide sequence |
|---|---|
| 1–20 | Ac-O1XXXXX-NH2 |
| 21–40 | Ac-XO2XXXX-NH2 |
| 41–60 | Ac-XXO3XXX-NH2 |
| 61–80 | Ac-XXXO4XX-NH2 |
| 81–100 | Ac-XXXXO5X-NH2 |
| 101–120 | Ac-XXXXXO6-NH2 |
a
The 120 peptide mixtures of a hexapeptide library are synthesized with specific amino acids at one of six positions in the peptide (O1, O2, O3, O4, O5, or O6) and five random amino acids (X) using the amino acid mixture described in Table 9.5.3. Ac, acetyl; see Table A.1B.1 for single-letter amino acid codes.