Fig. 2.

STING-dependent gene regulation in E17 Sting^−/− DNase II^−/−embryos. (A) STING and DNase II expression by qPCR and Western blot from E17 fetal liver wild-type (eWT), Sting^−/− DNase II^+/+(eStingKO), Sting^+/− DNase II^−/− (eDNaseIIKO), and Sting^−/− DNase II^−/− (eDoubleKO) embryos. (B) Macroscopic view of E17 Sting^+/− DNase II^+/−(Left), eDNaseIIKO (Center), and eDoubleKO (Right) embryos. (C) H&E and TUNEL stains from mice livers same as A. Feulgen stain of BMDM after incubation with thymocytes (+) Dex. (Magnification: 200×.)