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. 2012 Nov 6;109(47):19196–19201. doi: 10.1073/pnas.1206376109

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Fig. 4. — Dereplicating bioactives from Bacillus sp. (A) IVIS bioluminescence imaging of crude fermentation extracts of Bacillus sp. against S. aureus (Xen29 strain), following HPLC fractionation. (B) LC-MS/MS chromatogram of Bacillus sp. extract. Total-ion chromatograms (TICs) for MS and MS(n) are shown; bioactive wells are highlighted. (C) iSNAP dereplication results identifying a series of tyrocidines from the inputted LC-MS/MS data file in .mzXML format. Rt, retention time. (D) Extracted-ion chromatogram (EIC) of the five dereplicated tyrocidines.