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. 2012 Nov 21;12:107. doi: 10.1186/1471-2261-12-107

Table 1.

Characteristics of the studies included in the metanalysis

Author Number of patients and mean Age (years) Males (%) statin/control group Intervention Follow-up Total cholesterol (TC) and LDL cholesterol values before and after treatment with statin,mean mg/dl and % reduction Co-morbidities (%) statin/control group Concurrent Medications (%) statin/control group Placebo-controlled/Double blind Unsuccessful Cardioversion statin/control group (n) Mean Left Atrial diameter (mm) Statin/control group Jadad Score
Almroth 2009[21]
234 (65±10)
76/74
Atorvastatin 80 mg/day (started at least 14 days before EC)
30 days
TC:202–136 (−32.6%)
H:47/48 D:7/10 CAD:4/4
B:87/80 C:14/16 DG:16/20
YES/YES
8/13
44/43
5
LDL:123–65 (−52.8%)
Ozaydin 2006[22]
48 (62±11)
71/50
Atorvastatin 10 mg/day (started 48 hours before EC)
3 months
TC:179–151 (−15.6%)
H:42/38 D:21/25
B:33/25 C:21/42 DG:4/4 A:8/4 P:8/8
NO/NO
0
47/43
2
LDL:109–95 (−12.8%)
Xia 2009[23]
64 (61±8)
69/63
Rosuvastatin 10 mg/day (started 48 h before EC)
3 months
TC:159–131 (−17.6%)
-
B:38/31 C:31/34 A:22/28 DG:13/6
NO/NO
0
41/41
1
LDL:97–83 (−14.4%)
Tveit 2004[20]
114 (68±10)
79/75
Pravastatin 40 mg/day (started 3 weeks before EC)
6 weeks
Mean n.s.
H:42/44 D:9/4 COPD:11/11 CHD:9/12
B:67/65 C:30/28 DG:25/23 F:6/4 A:2/4
NO/NO
11/11
45/43
3
TC:-22%
LDL:-33%
Demir 2011[25]
44 (61±10)
48/44
Atorvastatin 40 mg/day (started 3 weeks before EC)
2 months
TC:174–129 (−25.8%)
H:74/52 D:8/4 S:17/17 CHD:21/13
A:91/87 P:4/8 C:22/26
NO/NO
1/1
42/43
1
LDL:112–62 (−44.6%)
Negi 2011[24] 64 (55±12) 82/84 Atorvastatin 80 mg/day (started at randomization: 0–7 days before EC) 12 months TC:183–142 (−22.4%) H:52/49 D:12/3.2 S:24/16 CHD:12/13 B: 49/68 YES/YES - 46/46 4

H, hypertension; D, diabetes mellitus; S: smoking; COPD, chronic obstructive pulmonary disease; CHD, coronary heart disease; B, beta blockers; C, calcium channel blockers; DG, Digitoxin; F, Flecainide; A, Amiodarone; P, Propafenone; n.s., not specified.