Table 1.
Author | Number of patients and mean Age (years) | Males (%) statin/control group | Intervention | Follow-up | Total cholesterol (TC) and LDL cholesterol values before and after treatment with statin,mean mg/dl and % reduction | Co-morbidities (%) statin/control group | Concurrent Medications (%) statin/control group | Placebo-controlled/Double blind | Unsuccessful Cardioversion statin/control group (n) | Mean Left Atrial diameter (mm) Statin/control group | Jadad Score |
---|---|---|---|---|---|---|---|---|---|---|---|
Almroth 2009[21] |
234 (65±10) |
76/74 |
Atorvastatin 80 mg/day (started at least 14 days before EC) |
30 days |
TC:202–136 (−32.6%) |
H:47/48 D:7/10 CAD:4/4 |
B:87/80 C:14/16 DG:16/20 |
YES/YES |
8/13 |
44/43 |
5 |
LDL:123–65 (−52.8%) | |||||||||||
Ozaydin 2006[22] |
48 (62±11) |
71/50 |
Atorvastatin 10 mg/day (started 48 hours before EC) |
3 months |
TC:179–151 (−15.6%) |
H:42/38 D:21/25 |
B:33/25 C:21/42 DG:4/4 A:8/4 P:8/8 |
NO/NO |
0 |
47/43 |
2 |
LDL:109–95 (−12.8%) | |||||||||||
Xia 2009[23] |
64 (61±8) |
69/63 |
Rosuvastatin 10 mg/day (started 48 h before EC) |
3 months |
TC:159–131 (−17.6%) |
- |
B:38/31 C:31/34 A:22/28 DG:13/6 |
NO/NO |
0 |
41/41 |
1 |
LDL:97–83 (−14.4%) | |||||||||||
Tveit 2004[20] |
114 (68±10) |
79/75 |
Pravastatin 40 mg/day (started 3 weeks before EC) |
6 weeks |
Mean n.s. |
H:42/44 D:9/4 COPD:11/11 CHD:9/12 |
B:67/65 C:30/28 DG:25/23 F:6/4 A:2/4 |
NO/NO |
11/11 |
45/43 |
3 |
TC:-22% | |||||||||||
LDL:-33% | |||||||||||
Demir 2011[25] |
44 (61±10) |
48/44 |
Atorvastatin 40 mg/day (started 3 weeks before EC) |
2 months |
TC:174–129 (−25.8%) |
H:74/52 D:8/4 S:17/17 CHD:21/13 |
A:91/87 P:4/8 C:22/26 |
NO/NO |
1/1 |
42/43 |
1 |
LDL:112–62 (−44.6%) | |||||||||||
Negi 2011[24] | 64 (55±12) | 82/84 | Atorvastatin 80 mg/day (started at randomization: 0–7 days before EC) | 12 months | TC:183–142 (−22.4%) | H:52/49 D:12/3.2 S:24/16 CHD:12/13 | B: 49/68 | YES/YES | - | 46/46 | 4 |
H, hypertension; D, diabetes mellitus; S: smoking; COPD, chronic obstructive pulmonary disease; CHD, coronary heart disease; B, beta blockers; C, calcium channel blockers; DG, Digitoxin; F, Flecainide; A, Amiodarone; P, Propafenone; n.s., not specified.