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Schematics of zinc finger nucleases cleaving HPV type 18 genomic DNA. This figure offers a diagrammatic illustration of loci of action of zinc finger nucleases that target and cleave >18 bp (9x2 + 5, 6, or 7) sequences within the genomic DNA context of HPV type 18. Hits (blue, green, and gold bars) represent targets along the gene (red bars). ZFN hits in the graphic are color-coded on the basis of spacer size (5 bp = Blue; 6 bp = Green; 7 bp = Gold).
