Table 3.
Coronary heart disease risk parameter changes during the weight loss period1
| |
|
IFCR-L |
|
|
IFCR-F |
|
|---|---|---|---|---|---|---|
| Week 3 | Week 10 | Change2 | Week 3 | Week 10 | Change2 | |
| Systolic BP (mm Hg) |
120 ± 3 |
118 ± 2 |
−2 ± 6 |
116 ± 4 |
114 ± 2 |
−2 ± 4 |
| Diastolic BP (mm Hg) |
83 ± 3 |
79 ± 3 |
−4 ± 4 |
80 ± 3 |
80 ± 2 |
0 ± 3 |
| Heart rate (bpm) |
73 ± 3 |
70 ± 4 3 |
−3 ± 4 4 |
78 ± 2 |
81 ± 2 |
3 ± 2 |
| Glucose (mg/dl) |
120 ± 2 |
116 ± 2 3 |
−4 ± 3 |
120 ± 3 |
117 ± 3 |
−3 ± 4 |
| Insulin (uIU/ml) |
14 ± 1 |
11 ± 1 3 |
−3 ± 3 |
15 ± 2 |
13 ± 2 |
−2 ± 2 |
| C-Reactive protein (mg/dl) |
0.4 ± 0.1 |
0.4 ± 0.1 |
0 ± 0.1 |
0.6 ± 0.2 |
0.4 ± 0.1 |
−0.2 ± 0.2 |
| Homocysteine (ng/dl) |
10 ± 1 |
8 ± 1 3 |
−2 ± 1 4 |
10 ± 1 |
10 ± 1 |
0 ± 1 |
| Adiponectin (ng/ml) |
7893 ± 1002 |
5462 ± 576 3 |
−2431 ± 802 |
8442 ± 1201 |
5931 ± 964 3 |
−2511 ± 771 |
| Leptin (ng/ml) | 37 ± 3 | 27 ± 3 3 | −10 ± 2 | 38 ± 2 | 29 ± 2 3 | −9 ± 2 |
1 Values reported as mean ± SEM. IFCR-L: Intermittent fasting calorie restriction-liquid diet (n = 28); IFCR-F: Intermittent fasting calorie restriction-food based diet (n = 26); BP: Blood pressure.
2 Change expressed as the difference between week 3 and week 10 absolute values.
3 Week 3 values significantly (P < 0.05) different from week 10 values within group (Repeated-measures ANOVA).
4 Absolute change significantly different (P < 0.05) between the IFCR-L and IFCR-F group (Repeated-measures ANOVA).