Table 3.
Strain | Inoculum | Right joint diameter (mm) (Avg±SD) | Right Tibiotarsus inflammation | Right knee/Tibial crest (Tc) inflammation |
---|---|---|---|---|
B31 |
10 |
4.07±0.06 |
-, ±, + |
-, -, - |
102 |
3.90±0.20 |
-, ±, + |
-, -, + (Tc) |
|
103 |
5.10±0.00 |
3+, 3+ |
+, +, |
|
104 |
4.90±0.00 |
3+, 3+ |
+, + |
|
N40 | 10 |
4.03±0.15 |
-, 2+, 3+ |
-, +, + |
102 |
4.60±0.17 |
+, 2 to 3+, 3+ |
+(Tc), +, + |
|
103 |
4.75±0.07 |
3+, 3+ |
+, +, |
|
104 | 5.00±0.00 | 3+, 3+ | +, + |
Joint swelling of each dose was quantitated by average diameter of the right tibiotarsal joint of multiple mice with each dose group. Joint inflammation was scored from “-” (no arthritis) to “+++ (3+)” (severe arthritis) in the tibiotarsus for infected mice at each inoculation dose. Knee or Tibial crest (Tc) inflammation was recorded as “-” (no arthritis) to “+” (arthritis) of each infected mouse.