. 2012 Nov 30;7(11):e50803. doi: 10.1371/journal.pone.0050803

Table 3. Multivariate Cox-PH Model for the Risk of Stroke in Subjects With and Without Depression (GDS ≥5)/Antidepressant Medication, Adjusted for Known Risk Factors^*.

	Age <65				Age ≥65				All
	Events/N	HR	95% CI	P-value (Wald)	Events/N	HR	95% CI	P-value (Wald)	Events/N	HR	95% CI	P-value (Wald)
GDS ≥5	24/1609	3.23	1.19 to 8.81	0.022	131/2110	1.09	0.70 to 1.69	0.715	155/3727	1.20	0.80 to 1.79	0.380
Antidepressant	24/1609	1.67	0.38 to 7.34	0.498	131/2110	0.89	0.47 to 1.68	0.712	155/3727	0.94	0.52 to 1.68	0.826
GDS ≥5 or antidepressant	24/1609	2.84	1.11 to 7.29	0.030	131/2110	1.20	0.80 to 1.79	0.380	155/3727	1.30	0.90 to 1.89	0.158

Adjusted for age, sex, BMI, smoking, hypertension, diabetes, hyperlipidemia, previous myocardial infarction, previous TIA, previous stroke, history of atrial fibrillation, and physical activity.

HR, hazard ratio.

Table 3. Multivariate Cox-PH Model for the Risk of Stroke in Subjects With and Without Depression (GDS ≥5)/Antidepressant Medication, Adjusted for Known Risk Factors*.

Table 3. Multivariate Cox-PH Model for the Risk of Stroke in Subjects With and Without Depression (GDS ≥5)/Antidepressant Medication, Adjusted for Known Risk Factors^*.