Table 7. Normal Ig and absence of auto-antibodies in young Eps15-KO mice.

	Male (n = 15, each)		Female (n = 15, each)
	Eps15-WT	Eps15-KO	Eps15-WT	Eps15-KO
IgG1	167.3±16.4	191.4±17.8	130.1±13.0	162.3±14.0
IgG2a	83.3±14.0	70.0±8.1	64.2±7.5	54.8±7.9
IgG2b	171.5±29.2	246.1±28.5	284.3±35.4	398.2±45.7
IgG3	99.1±15.2	170.9±45.1	145.7±18.8	96.8±20.2
IgM	1002.0±203.7	886.5±171.3	784.4±29.2	722.7±115.6
IgA	336.5±148.4	234.3±47.1	150.0±20.5	134.4±20.7
Anti-DNA Ab	0	0	0	0
Rheumatoid factor	0	0	0	0

Antibody titers were determined in serum from 12-week old mice.