Skip to main content
. 2012 Nov 30;7(11):e50699. doi: 10.1371/journal.pone.0050699

Figure 3. Role of serine catabolism in C. jejuni 81-176 mouse colonization.

Figure 3

Shown is the colonization efficiency of C. jejuni 81-176 wild-type (black diamonds) and its isogenic sdaA mutant strain (white diamonds) in a murine model of infection. The colonization of the intestine (A) and liver (B) was evaluated 5 weeks after oral or intraperitoneal co-infection of myd88−/− nramp−/− mice, respectively. Each pair of black and white diamonds represents the CFU numbers of the C. jejuni 81-176 wild-type strain and its sdaA mutant recovered from the indicated organs of an individual animal. The combined results of one (A) and two (B) independent infection experiments are shown. The Mann–Whitney U test ( = Wilcoxon rank-sum test) was used to calculate the P values for the statistical differences between the CFU numbers of the different strains: P<0.05 (A) and P<0.001 (B).