Table 1. Average number of individual somatic signs assessed in CaMKIV +/+ and −/− mice.

Groups	Paw tremor	Body tremor	Head shakes	Backing	Others
veh/veh CaMKIV +/+	1.2±0.2	0	0.4±0.2	0	0
veh/mec CaMKIV +/+	1.2±0.7	0	0.3±0.3	0.5±0.3	0
nic/mec CaMKIV +/+	7.2±1.1*	2±0.6*	5.8±2.2*	2.8±1.0*	0.4±0.2*
veh/veh CaMKIV −/−	0.6±0.4	0	0.4±0.2	0	0
veh/mec CaMKIV −/−	1.3±0.5	0	1.75±1.1	0.25±0.3	0
nic/mec CaMKIV −/−	12.6±0.8* +	2±0.5*	2.6±0.2	2.8±0.3*	0.4±0.4*

Each point represents the mean ± SEM of 4–6 mice per group. The heading “others” refers to jumps, curls, and ptosis.

^*denotes p<0.05 vs. corresponding vehicle groups. + denotes p<0.05 vs. CamKIV nic/mec +/+ mice. veh, vehicle; nic, nicotine; mec, mecamylamine.