Table 2. Variants in the CaMKIV gene are associated with nicotine dependence.

Phenotype	SNP	Allele	P-value	Beta/OR	Q p-value
FTND	rs919334	C	0.01	−0.185	0.41
	rs1457115	A	0.53	−0.044	0.51
	rs9285875	T	0.04	0.163	0.82
numCIG	rs919334	C	0.17	−0.034	0.20
	rs1457115	A	0.95	−0.001	0.45
	rs9285875	T	0.43	0.021	0.88
FTND1	rs919334	C	0.14	−0.045	0.06
	rs1457115	A	0.11	0.046	0.86
	rs9285875	T	0.63	−0.015	0.56
FTND5	rs919334	C	0.33	0.94	0.02
	rs1457115	A	0.50	1.04	0.72
	rs9285875	T	0.87	1.01	0.08

Human genetic association meta-analysis using two datasets (SAGE and MGS, n = 3,969). The variant rs919334 is associated with a protective effect in the FTND score analysis, while rs9285875 is associated with risk for higher FTND scores. The table contains uncorrected p-values, where significant p- values are bolded and underlined. No markers survived correction for multiple testing. Significant Q p-values are italicized. SNP, single nucleotide polymorphism; the Allele column represents the minor allele; Q p-values represent Cochrane’s Q-statistic p-values.