Figure 2. Top Panel: Scatter plot of pooled ASPS-tissue (y-axis) versus ASPS-1 (x-axis) differential gene expression measurements.

Data trimming (see Methods: Statistical Analysis) reduced the original 54,798 measurements to 17,698 differentially expressed genes. The diagonal line represents the first principal component (1^st PC) from PCA analysis and accounts for 91% of the variation in this data set. The lower panel displays the 1244 gene expressions not associated with the 1^st PC. Points in red and green, respectively, correspond to differential expressions relatively higher in the pooled ASPS-tissue versus ASPS-1 gene expressions, and vice-versa. Consistent with the PCA analysis, the 1^st PC exactly bisects the pooled ASPS-tissue versus ASPS-1 datasets.