Table 2. Summary of Grade 3 or 4 Treatment-related Adverse Events.
| NCI CTCAE 3.0 Category/Term | Grade 3 Number | Grade 4 Number |
| Any event | 12 | 7 |
| Ocular/Visual | ||
| Blurred vision | 1 | 0 |
| Cataract | 1 | 0 |
| Constitutional | ||
| Fatigue | 1 | 0 |
| Gastrointestinal | ||
| Diarrhea | 2 | 0 |
| Mucositis, functional: pharynx | 1 | 0 |
| Metabolic/Laboratory | ||
| Hypocalcemia | 1 | 0 |
| Blood/Bone Marrow | ||
| Hemoglobin | 1 | 1 |
| Leukocytes | 2 | 2 |
| Lymphopenia | 1 | 1 |
| Neutrophils | 4 | 6 |
| Platelets | 3 | 1 |
| Neurology | ||
| Neuropathy-sensory | 2 | 0 |
| Infection | ||
| Febrile neutropenia | 0 | 1 |
| Urinary Tract Infection with Grade 3–4 ANC | 1 | 0 |
| Dermatology/Skin | ||
| Pruritus | 1 | 0 |
| Rash | 5 | 0 |
Abbreviations: ANC, Absolute Neutrophil Count; CTCAE, Common Terminology Criteria for Adverse Events; NCI, National Cancer Institute.