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Hematoxylin and eosin stain (H&E) of the skin lesion indicated a keratinocytes degeneration and necrosis, subepidermal bulla with infiltration of a few inflammatory cells (A, magnification×40; B×100). Under transmission electron microscope, the split was located at the sub-lamina densa where some red blood cells could be seen (asterisk) (C). The arrow refers to the lamina densa. Magnification×10000.
