Table 2. HPV Genotyping of Anal Tissues: Overall Prevalence and Across the Spectrum of Anal Neoplasia.

HPV Type	Overall HPV Prevalence* (n = 24 Patients)	Normal Mucosa (n = 3 Tissues)	SCC-in Situ (n = 11 Tissues)	SCC (n = 15 Tissues)
High Risk
HPV-16	22 (92%)	3 (100%)	6 (54%)	13 (87%)
HPV-18	1 (4%)	–	1 (9%)	–
HPV-31	1 (4%)	–	1 (9%)	–
HPV-39	2 (8%)	–	1 (9%)	1 (7%)
HPV-52	6 (25%)	–	4 (36%)	2 (13%)
HPV-54	1 (4%)	–	1 (9%)	–
Low Risk
HPV-6	3 (13%)	–	3 (27%)	–
HPV-11	2 (8%)	–	–	2 (13%)

^*A total of 38 HPV infections were detected in 29 tissues, due to multiple infections.