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. 2012 Nov 30;7(11):e50536. doi: 10.1371/journal.pone.0050536

Figure 4. miR-218 over-expression causes a delay in early heart field migration.

Figure 4

A,B, images of Tg(cmlc2:eGFP) embryos injected with 260 pg of miR-Ct (A) or with 260 pg of miR-218a mimic (B) at different times of development. Dorsal view, anterior at the bottom. After confocal analysis, embryos were left to develop until 72 hpf when they were screened for the presence of edema. White scale bars: 150 µm. C, migration velocities of myocardial Tg(cmlc2:eGFP) cells as quantified from time-lapse images. Five embryos for each experiment were analyzed.