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. 2012 Nov 30;7(11):e50411. doi: 10.1371/journal.pone.0050411

Table 1. The percentage of gene pairs in the same pathway when p-value thresholds ranging from 1.0×10−35 to 1.0×10−5 were applied to cut off correlated lists of gene pairs resulting from eight methods.

Methods\P value 1.0E-35 1.0E-25 1.0E-15 1.0E-05 0.05
Kendall 2.51% (25,485) 2.51% (25,499) 1.76% (41,749) 0.25% (1,364,076) 0.15% (5,272,820)
Spearman 12.87% (404) 5.31% (1,611) 1.13% (87,116) 0.24% (1,472,610) 0.15% (5,312,831)
Rank Theil-Sen / / 0.30% (886,264) 0.15% (5,112,691) 0.13% (8,032,269)
Hoeffding / / / / 0.14% (6,927,518)
Weighted Rank / / / 0.26% (1,279,295) 0.15% (5,287,220)
Theil-Sen / / 0.36% (636,501) 0.16% (4,695,948) 0.13% (7,847,207)
Pearson 1.02% (17,701) 1.09% (49,630) 0.71% (200,325) 0.24% (1,725,471) 0.15% (5,486,544)
Distance Covariance / / / / 0.16% (4,264,095)

(The numbers shown in parentheses are gene pairs in cut-off lists by p values).