Table II.
Type of Sample | Healthy volunteers | Asthmatics |
---|---|---|
| ||
BAL fluids | n=5 | n=5 |
Mean age : 31.6 yrs [range 20-55 yrs] | Mean age : 32.0 yrs [range 20-37 yrs] | |
FEV1% predicted : 102.0 ± 5.5 [±sem] | FEV1% predicted : 97.1 ± 7.3 [±sem] | |
| ||
No medications | Albuterol prn only | |
| ||
Endobronchial biopsy | n=5 | n=10 |
Mean age : 24.4yrs [range 18-35 yrs] | Mean age : 37.9 yrs [range 18-56 yrs] | |
FEV1% predicted : 104.8 ± 3.5 [±sem] | FEV1% predicted : 83.7 ± 3.9 [±sem] | |
| ||
No medications | Inhaled steroids (at least 2000 ug beclometasone or equivalent), inhaled long acting beta agonists and at least one other asthma therapy (oral LTRA, theophylline, or oral steroids) |
All human research was conducted under permission granted by Southampton and South West Hampshire Research Ethics Committees.