Fig. 3.

Haplotypes from the linkage disequilibrium (LD) block that includes the nonsynonymous “A”/“G” SNP at chr3:44,706,389 (indicated by the asterisk). This haplotype block is indicated as “2” in Fig. 2 and spans the large first and second introns of IGF1R. The 50 SNPs are shown as columns and alleles are shaded. The bar graphs on the right show the total number of chromosomes carrying each haplotype for each of two groups of breeds: “Tiny” = 13 breeds in which the average adult male’s height at the withers is no more than 10 in., and “Big” = 15 breeds with average adult male’s height at the withers of at least 25 in. See also Supplementary Fig. 3 for breed-by-breed counts of chromosomes for each haplotype