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Situations in which to consider use of antimicrobial therapy following incision and debridement of a CA-MRSA SSTI.
| Severe or extensive disease and/or rapid progression in presence of associated cellulitis |
| Signs and symptoms of systemic illness |
| Associated comorbidities or immune suppression (DM, HIV/AIDS, neoplastic disease) |
| Extremes of age |
| Abscess in area difficult to drain |
| Associated septic phlebitis |
| Lack of response of treatment with incision and drainage alone |
