Table 3.
Top 15 of differentially expressed genes, between badversusgood outcome PDAC samples
| Gene Symbol | Gene name | Fold bad/good | P-value |
|---|---|---|---|
| CPB1 |
Carboxypeptidase B1 |
31.03 |
3.16E-05 |
| CTRB2 |
Chymotrypsinogen B2 |
24.38 |
2.78E-05 |
| PLA2G1B |
Phospholipase A2, group IB, pancreas |
20.35 |
0.00022 |
| PNLIPRP2 |
Pancreatic lipase-related protein 2 |
19.48 |
0.00019 |
| PNLIP |
Pancreatic lipase |
19.06 |
0.00048 |
| CEL |
Carboxyl ester lipase (bile salt-stimulated lipase) |
18.89 |
0.00011 |
| CPA1 |
Carboxypeptidase A1, pancreatic |
18.57 |
6.68E-05 |
| CELA3A |
Chymotrypsin-like elastase family, member 3A |
17.10 |
2.47E-05 |
| CELA3B |
Chymotrypsin-like elastase family, member 3B |
16.56 |
2.01E-05 |
| CPA2 |
Carboxypeptidase A2 (pancreatic) |
14.43 |
0.00016 |
| CLPS |
Colipase, pancreatic |
11.55 |
0.00035 |
| CTRC |
Chymotrypsin C (caldecrin) |
11.17 |
0.00023 |
| KRT6A |
Keratin 6A |
10.23 |
0.00090 |
| PRSS2 |
Protease, serine, 2 (trypsin 2) |
8.87 |
0.00092 |
| DEFA5 |
Defensin, alpha 5, Paneth cell-specific |
−13.95 |
9.04E-08 |
| SLC26A3 |
Solute carrier family 26, member 3 |
−13.76 |
4.08E-08 |
| SI |
Sucrase-isomaltase (alpha-glucosidase) |
−8.95 |
2.29E-07 |
| TAC3 |
Tachykinin 3 |
−8.06 |
0.00029 |
| PRSS7 |
Protease, serine, 7 (enterokinase) |
−6.93 |
1.99E-08 |
| DEFA6 |
Defensin, alpha 6, Paneth cell-specific |
−6.50 |
1.50E-06 |
| VIP |
Vasoactive intestinal polypeptide |
−6.12 |
1.82E-05 |
| RBP2 |
Retinol binding protein 2, cellula |
−5.68 |
1.72E-07 |
| UGT2B17 |
UDP glucuronosyltransferase 2 family, polypeptide B17 |
−5.33 |
0.00090 |
| CDH19 |
Cadherin 19, type 2 |
−4.90 |
0.00089 |
| SYNM |
Synemin, intermediate filament protein |
−4.86 |
1.53E-05 |
| FOXA1 |
Forkhead box A1 |
−4.30 |
6.00E-07 |
| CLCA1 |
Chloride channel accessory 1 |
−3.90 |
2.05E-05 |
| ELF5 |
E74-like factor 5 |
−3.74 |
1.50E-06 |
| AKR1C1 | Aldo-keto reductase family 1, member C1 | −3.63 | 0.00043 |