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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: J Bone Miner Res. 2013 Jan;28(1):46–55. doi: 10.1002/jbmr.1740

Figure 4. FGF23 suppresses expression of CYP27B1 in monocytes from peritoneal dialysates.

Figure 4

4A. Effect of FGF23 (100 ng/ml, 6hrs) on expression of mRNA for CYP27B1, CYP24A1, Klotho and FGFR1 in peritoneal dialysate monocytes (PDm). Data are shown as mean ± SEM fold-change in mRNA expression relative to vehicle-treated cells for PDm from n = 7 different donors. 4B. Immunofluorescence analysis of protein for Klotho (green), FGFR-1 (red) and nuclear DAPI (blue) in PDm. Merged immunofluoresence shows co-expression of FGFR1 and Klotho in PDm. * = statistically different from vehicle-treated PDm, p< 0.05.