Figure 7.
Probability distribution of inactive X chromosomes in XXXX and XXXY tetraploid cells. (Top panel) Probability distribution of the number of inactive X chromosomes, , in tetraploid XXXX cells. (Shaded bars) Experimental data (21). (Solid bars) Predictions in the different colocalization states (top of each panel). Colocalized state, corresponding to the configuration where two independent X couples are formed (top-left panel), best describes the data. (Bottom panel) Probability distribution of the number of inactive X chromosomes in tetraploid XXXY cells. (Shaded bars) Experimental data (21). (Solid bars) Predictions. Good agreement is found in the configurations where at least two X chromosomes are paired (bottom-left and central panels).