Table 6 . Components of the PAM complex: ATP-dependent pulling of proteins through the TIM23 complex into the matrix.

Protein	ORF	Known function	Null phenotype
Mdj2	YNL328C		Viable, various defects
Mge1	YOR232W	Nucleotide release factor for Ssc1	Inviable
Pam16	YJL104W		Inviable
Pam17	YKR065C	Interaction between TIM23 and PAM complexes	Viable
Pam18	YLR008C	J protein co-chaperone for Ssc1	Inviable
Ssc1	YJR045C	Hsp70; ATP hydrolysis drives import of substrates into matrix	Inviable