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. Author manuscript; available in PMC: 2012 Dec 3.
Published in final edited form as: Am J Physiol Cell Physiol. 2011 Jul 13;301(4):C872–C885. doi: 10.1152/ajpcell.00507.2010

Fig. 3.

Fig. 3

Rescue of F508del-CFTR by novel compounds. A,B: representative traces and summary of QR from HS-YFP assays on CFBE41o- cells expressing F508del-CFTR. Cells were treated with indicated compounds: 9-aminoacridine (9-AC, 5 μM), ciclopirox (CPX, 20 μM), SAHA (5 μM) (n = 5-12; *, p < 0.05). C-F: representative recordings of transepithelial Cl− currents (C-E) and amplitude of inh-172-sensitive current (F) from CFBE41o- cells expressing F508del-CFTR treated with and without 9-AC or SAHA (n = 6-10; *, p < 0.05).